,Tweet Facebook Mail Victorian researchers are about to investigate whether an existing drug could reduce knee pain in osteoarthritis sufferers. Knee pain sufferers will take the antidepressant Amitriptyline in a low dose during the three-month trial, and researchers will examine whether the medication is effective. The study would aim to “try and turn down the volume of pain”, Monash University Associate Professor Anita Wluka said. Mr Trapani suffers knee pain. (9NEWS)“Sometimes where there’s been inflammation and damage for a long time the nerves are switched on and it doesn’t take much to set the pain off,” she said. The drug has also been used to treat shingles, diabetes-related nerve pain, and back pain “It’s been used as an anti-depressant but in much higher doses than we’re using know,” Assoc. Prof. Wluka said. Osteoarthritis sufferer Tony Trapani, 56, said he was eager for a more effective treatment. RelatedNew high-tech living transforming the lives of retireesJack the dinosaur makes a move to new homePush to rename Yarra River to correct 19th Century mistranslation“It’s a really nagging pain, it’s just there all the time whether I'm standing or sitting now, whether I’m walking or trying to do sport,” he said. “Anything that can remove the pain, that makes me a bit more mobile is going to be off great benefit to me… one of the catch 22’s with all this is that because you’ve got the pain it limits the amount of exercise you can do.”Researchers are in the process of recruiting 150 people aged been 40 and 70 years to participate in the three-month trial through the Alfred Hospital. For more information about the trial, visit the Monash website.
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